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Structure paper

TitleProtein-induced photophysical changes to the amyloid indicator dye thioflavin T.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 16863-16868, Year 2010
Publish dateMay 11, 2010 (structure data deposition date)
AuthorsWolfe, L.S. / Calabrese, M.F. / Nath, A. / Blaho, D.V. / Miranker, A.D. / Xiong, Y.
External linksProc. Natl. Acad. Sci. USA / PubMed:20826442
MethodsX-ray diffraction
Resolution1.6 - 2.7 Å
Structure data

PDB-3myz:
Protein induced photophysical changes to the amyloid indicator dye, thioflavin T
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-3mzt:
Protein-induced photophysical changes to the amyloid indicator dye, thioflavin T
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HG:
Unknown entry

ChemComp-TFX:
2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-CU:
COPPER (II) ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / amyloid / Thioflavin T / Parkinson's / Alzheimer's / beta-2 microglobulin

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