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TitleA structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions.
Journal, issue, pagesJ. Mol. Biol., Vol. 403, Page 351-370, Year 2010
Publish dateMay 25, 2010 (structure data deposition date)
AuthorsLuncsford, P.J. / Chang, D.Y. / Shi, G. / Bernstein, J. / Madabushi, A. / Patterson, D.N. / Lu, A.L. / Toth, E.A.
External linksJ. Mol. Biol. / PubMed:20816984
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-3n5n:
Crystal structure analysis of the catalytic domain and interdomain connector of human MutY homologue
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / alpha-helices / helix-hairpin-helix motif / iron-sulfur cluster

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