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TitleProtective efficacy of cross-reactive CD8+ T cells recognising mutant viral epitopes depends on peptide-MHC-I structural interactions and T cell activation threshold.
Journal, issue, pagesPlos Pathog., Vol. 6, Page e1001039-e1001039, Year 2010
Publish dateJan 12, 2009 (structure data deposition date)
AuthorsValkenburg, S.A. / Gras, S. / Guillonneau, C. / La Gruta, N.L. / Thomas, P.G. / Purcell, A.W. / Rossjohn, J. / Doherty, P.C. / Turner, S.J. / Kedzierska, K.
External linksPlos Pathog. / PubMed:20711359
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-3ftg:
Crystal Structure of H2Db in complex with NP366-N3A variant peptide from influenza
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / H2Db / mouse MHC / influenza / immunology / Glycoprotein / Immune response / Membrane / MHC I / Transmembrane / Immunoglobulin domain / Secreted

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