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TitleBiological and structural characterization of a host-adapting amino acid in influenza virus.
Journal, issue, pagesPlos Pathog., Vol. 6, Page e1001034-e1001034, Year 2010
Publish dateOct 20, 2009 (structure data deposition date)
AuthorsYamada, S. / Hatta, M. / Staker, B.L. / Watanabe, S. / Imai, M. / Shinya, K. / Sakai-Tagawa, Y. / Ito, M. / Ozawa, M. / Watanabe, T. ...Yamada, S. / Hatta, M. / Staker, B.L. / Watanabe, S. / Imai, M. / Shinya, K. / Sakai-Tagawa, Y. / Ito, M. / Ozawa, M. / Watanabe, T. / Sakabe, S. / Li, C. / Kim, J.H. / Myler, P.J. / Phan, I. / Raymond, A. / Smith, E. / Stacy, R. / Nidom, C.A. / Lank, S.M. / Wiseman, R.W. / Bimber, B.N. / O'Connor, D.H. / Neumann, G. / Stewart, L.J. / Kawaoka, Y.
External linksPlos Pathog. / PubMed:20700447
MethodsX-ray diffraction
Resolution2.05 - 2.3 Å
Structure data

PDB-3kc6:
Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/viet nam/1203/2004 (h5n1)
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-3khw:
Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/mexico/indre4487/2009(h1n1)
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3l56:
Crystal structure of the large c-terminal domain of polymerase basic protein 2 from influenza virus a/viet nam/1203/2004 (h5n1)
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • influenza a virus (a/viet nam/1203/2004(h5n1))
  • influenza a virus (a/mexico/indre4487/2009(h1n1))
  • influenza a virus
KeywordsVIRAL PROTEIN / Bird flu / structural genomics / NIAID / mRNA capping / mRNA processing / Seattle Structural Genomics Center for Infectious Disease / SSGCID / PB2 c-terminal domain / Swine Flu / H1N1 / H5N1 / PB2 / polymerase / Host mitochondrion

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