+Search query
-Structure paper
Title | The Sugar Ring of the Nucleoside Is Required for Productive Substrate Positioning in the Active Site of Human Deoxycytidine Kinase (dCK): Implications for the Development of dCK-Activated Acyclic Guanine Analogues. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 53, Page 5792-5800, Year 2010 |
Publish date | Apr 13, 2010 (structure data deposition date) |
Authors | Hazra, S. / Konrad, M. / Lavie, A. |
External links | J. Med. Chem. / PubMed:20684612 |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | PDB-3mjr: |
Chemicals | ChemComp-AC2: ChemComp-UDP: ChemComp-HOH: |
Source |
|
Keywords | TRANSFERASE / ACV / GCV / dCK / Kinase / UDP / P-Loop / kinase activity / nucleoside kinase |