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| Title | The Sugar Ring of the Nucleoside Is Required for Productive Substrate Positioning in the Active Site of Human Deoxycytidine Kinase (dCK): Implications for the Development of dCK-Activated Acyclic Guanine Analogues. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 53, Page 5792-5800, Year 2010 |
| Publish date | Apr 13, 2010 (structure data deposition date) |
Authors | Hazra, S. / Konrad, M. / Lavie, A. |
External links | J. Med. Chem. / PubMed:20684612 |
| Methods | X-ray diffraction |
| Resolution | 2.1 Å |
| Structure data | ![]() PDB-3mjr: |
| Chemicals | ![]() ChemComp-AC2: ![]() ChemComp-UDP: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSFERASE / ACV / GCV / dCK / Kinase / UDP / P-Loop / kinase activity / nucleoside kinase |
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homo sapiens (human)
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