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TitleCorecognition of DNA and a methylated histone tail by the MSL3 chromodomain.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 17, Page 1027-1029, Year 2010
Publish dateMar 22, 2010 (structure data deposition date)
AuthorsKim, D. / Blus, B.J. / Chandra, V. / Huang, P. / Rastinejad, F. / Khorasanizadeh, S.
External linksNat. Struct. Mol. Biol. / PubMed:20657587
MethodsX-ray diffraction
Resolution1.29 - 2.35 Å
Structure data

PDB-3m9q:
Drosophila MSL3 chromodomain
Method: X-RAY DIFFRACTION / Resolution: 1.29 Å

PDB-3oa6:
Human MSL3 Chromodomain bound to DNA and H4K20me1 peptide
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-IMD:
IMIDAZOLE

Source
  • drosophila melanogaster (fruit fly)
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN / Chromodomain / MSL3 / methyllysine recognition / aromatic cage / MSL complex / transcription upregulation / DNA BINDING PROTEIN/DNA / histone H4 tail / DNA backbone recognition / H4K20me1 / DNA BINDING PROTEIN-DNA complex / DNA

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