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TitleStructure of the complex between HER2 and an antibody paratope formed by side chains from tryptophan and serine.
Journal, issue, pagesJ. Mol. Biol., Vol. 402, Page 217-229, Year 2010
Publish dateMay 27, 2010 (structure data deposition date)
AuthorsFisher, R.D. / Ultsch, M. / Lingel, A. / Schaefer, G. / Shao, L. / Birtalan, S. / Sidhu, S.S. / Eigenbrot, C.
External linksJ. Mol. Biol. / PubMed:20654626
MethodsX-ray diffraction
Resolution3.2 Å
Structure data

PDB-3n85:
Crystallographic trimer of HER2 extracellular regions in complex with tryptophan-rich antibody fragment
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsTransferase/immune system / HER2 / ERBB2 / Trp/Ser library / phage display / Transferase-immune system complex

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