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TitleInsights into eukaryotic DNA priming from the structure and functional interactions of the 4Fe-4S cluster domain of human DNA primase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 13684-13689, Year 2010
Publish dateJan 5, 2010 (structure data deposition date)
AuthorsVaithiyalingam, S. / Warren, E.M. / Eichman, B.F. / Chazin, W.J.
External linksProc. Natl. Acad. Sci. USA / PubMed:20643958
MethodsX-ray diffraction
Resolution1.698 Å
Structure data

PDB-3l9q:
Crystal structure of human polymerase alpha-primase p58 iron-sulfur cluster domain
Method: X-RAY DIFFRACTION / Resolution: 1.698 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / pol alpha / primase / DNA replication / polymerase / iron-sulfur cluster / DNA-binding / DNA-directed RNA polymerase / Iron / Iron-sulfur / Metal-binding / Nucleotidyltransferase / Phosphoprotein / Primosome / Transcription

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