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TitleThe Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Journal, issue, pagesStructure, Vol. 18, Page 1032-1043, Year 2010
Publish dateFeb 11, 2010 (structure data deposition date)
AuthorsLu, C. / Xu, H. / Ranjith-Kumar, C.T. / Brooks, M.T. / Hou, T.Y. / Hu, F. / Herr, A.B. / Strong, R.K. / Kao, C.C. / Li, P.
External linksStructure / PubMed:20637642
MethodsX-ray diffraction
Resolution2.15 - 2.6 Å
Structure data

PDB-3lrn:
Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3lrr:
Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHydrolase/RNA / Innate immunity / viral RNA sensing / RIG-I like receptors / Antiviral defense / ATP-binding / Helicase / Immune response / Metal-binding / Nucleotide-binding / RNA-binding / Hydrolase-RNA complex / viral RNA / Hydrolase

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