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Structure paper

TitleCrystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity.
Journal, issue, pagesEmbo J., Year 2010
Publish dateJun 12, 2010 (structure data deposition date)
AuthorsWang, H. / Morita, M. / Yang, X. / Suzuki, T. / Yang, W. / Wang, J. / Ito, K. / Wang, Q. / Zhao, C. / Bartlam, M. ...Wang, H. / Morita, M. / Yang, X. / Suzuki, T. / Yang, W. / Wang, J. / Ito, K. / Wang, Q. / Zhao, C. / Bartlam, M. / Yamamoto, T. / Rao, Z.
External linksEmbo J. / PubMed:20628353
MethodsX-ray diffraction
Resolution1.8 - 2.4 Å
Structure data

PDB-3ngn:
Crystal structure of the human CNOT6L nuclease domain in complex with AMP
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3ngo:
Crystal structure of the human CNOT6L nuclease domain in complex with poly(A) DNA
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3ngq:
Crystal structure of the human CNOT6L nuclease domain
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-AMP:
ADENOSINE MONOPHOSPHATE / AMP*YM

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-1PS:
3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PROTEIN-AMP COMPLEX / HYDROLASE/DNA / PROTEIN-ssDNA COMPLEX / HYDROLASE-DNA complex / alpha/beta sandwich fold

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