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-Structure paper
Title | Structure-Based Optimization of Potent Pdk1 Inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 20, Page 4095-, Year 2010 |
Publish date | Apr 23, 2010 (structure data deposition date) |
Authors | Angiolini, M. / Banfi, P. / Casale, E. / Casuscelli, F. / Fiorelli, C. / Saccardo, M.B. / Silvagni, M. / Zuccotto, F. |
External links | Bioorg. Med. Chem. Lett. / PubMed:20621725 |
Methods | X-ray diffraction |
Resolution | 2 - 2.3 Å |
Structure data | PDB-2xch: PDB-2xck: |
Chemicals | ChemComp-CKG: ChemComp-GOL: ChemComp-SO4: ChemComp-HOH: ChemComp-MH4: |
Source |
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Keywords | TRANSFERASE / PI3-KINASE SIGNALLING / SERINE/THREONINE-PROTEIN KINASE / ATP-BINDING |