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Structure paper

TitleStructural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 25875-25879, Year 2010
Publish dateFeb 28, 2010 (structure data deposition date)
AuthorsSiponen, M.I. / Wisniewska, M. / Lehtio, L. / Johansson, I. / Svensson, L. / Raszewski, G. / Nilsson, L. / Sigvardsson, M. / Berglund, H.
External linksJ. Biol. Chem. / PubMed:20592035
MethodsX-ray diffraction
Resolution1.92 - 3.102 Å
Structure data

PDB-3lyr:
Human Early B-cell Factor 1 (EBF1) DNA-binding domain
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

PDB-3mqi:
Human early B-cell factor 1 (EBF1) IPT/TIG domain
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3muj:
Early B-cell factor 3 (EBF3) IPT/TIG and dimerization helices
Method: X-RAY DIFFRACTION / Resolution: 1.92 Å

PDB-3n50:
Human Early B-cell factor 3 (EBF3) IPT/TIG and HLHLH domains
Method: X-RAY DIFFRACTION / Resolution: 3.102 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-NH4:
AMMONIUM ION

ChemComp-HOH:
WATER

ChemComp-EMC:
ETHYL MERCURY ION

ChemComp-TMO:
trimethylamine oxide

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION ACTIVATOR / immunoglobulin (Ig)-like domain / Structural Genomics / Structural Genomics Consortium / SGC / Activator / Developmental protein / DNA-binding / Metal-binding / Nucleus / Transcription / Transcription regulation / Zinc-finger / immunoglobulin like fold / DNA BINDING PROTEIN / Helix-loop-heliX / Beta-barrel / helix-loop-helix-loop-helix

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