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TitleThe MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer.
Journal, issue, pagesNat. Chem. Biol., Vol. 6, Page 595-601, Year 2010
Publish dateApr 14, 2010 (structure data deposition date)
AuthorsStewart, M.L. / Fire, E. / Keating, A.E. / Walensky, L.D.
External linksNat. Chem. Biol. / PubMed:20562877
MethodsX-ray diffraction
Resolution2.321 Å
Structure data

PDB-3mk8:
The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer
Method: X-RAY DIFFRACTION / Resolution: 2.321 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS/APOPTOSIS REGULATOR / MCL-1 / MCL-1 SAHB D / staple / SAHB / BCL-2 family / apoptosis / anti-apoptotic / APOPTOSIS-APOPTOSIS REGULATOR complex

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