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TitleIdentification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 27418-27428, Year 2010
Publish dateMay 5, 2010 (structure data deposition date)
AuthorsSun, T. / Hayakawa, K. / Bateman, K.S. / Fraser, M.E.
External linksJ. Biol. Chem. / PubMed:20558738
MethodsX-ray diffraction
Resolution2.1 - 2.2 Å
Structure data

PDB-3mwd:
Truncated Human ATP-Citrate Lyase with Citrate Bound
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3mwe:
Truncated Human ATP-Citrate Lyase with Tartrate Bound
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-TLA:
L(+)-TARTARIC ACID

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / ATP-grasp / phosphohistidine / organic acid / LYASE

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