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Structure paper

TitleEpsilon substituted lysinol derivatives as HIV-1 protease inhibitors.
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 20, Page 4065-4068, Year 2010
Publish dateMar 22, 2010 (structure data deposition date)
AuthorsJones, K.L. / Holloway, M.K. / Su, H.P. / Carroll, S.S. / Burlein, C. / Touch, S. / DiStefano, D.J. / Sanchez, R.I. / Williams, T.M. / Vacca, J.P. / Coburn, C.A.
External linksBioorg. Med. Chem. Lett. / PubMed:20547452
MethodsX-ray diffraction
Resolution1.8 Å
Structure data

PDB-3m9f:
HIV protease complexed with compound 10b
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-595:
N-[(1S,5S)-5-{[(4-aminophenyl)sulfonyl](3-methylbutyl)amino}-1-methyl-6-oxohexyl]-Nalpha-(methoxycarbonyl)-beta-phenyl-L-phenylalaninamide

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsTRANSFERASE / HIV / protease

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