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Structure paper

TitleProbing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues.
Journal, issue, pagesBiochemistry, Vol. 49, Page 5772-, Year 2010
Publish dateJun 14, 2010 (structure data deposition date)
AuthorsKillelea, T. / Ghosh, S. / Tan, S.S. / Heslop, P. / Firbank, S.J. / Kool, E.T. / Connolly, B.A.
External linksBiochemistry / PubMed:20527806
MethodsX-ray diffraction
Resolution2.72 Å
Structure data

PDB-2xhb:
Crystal structure of DNA polymerase from Thermococcus gorgonarius in complex with hypoxanthine-containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.72 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • thermococcus gorgonarius (archaea)
KeywordsTRANSFERASE/DNA / TRANSFERASE-DNA COMPLEX / REPLICATION / EXONUCLEASE / DNA DAMAGE / EXO MINUS

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