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Structure paper

TitleMutagenic conformation of 8-oxo-7,8-dihydro-2'-dGTP in the confines of a DNA polymerase active site.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 17, Page 889-890, Year 2010
Publish dateMar 26, 2010 (structure data deposition date)
AuthorsBatra, V.K. / Beard, W.A. / Hou, E.W. / Pedersen, L.C. / Prasad, R. / Wilson, S.H.
External linksNat. Struct. Mol. Biol. / PubMed:20526335
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3mby:
Ternary complex of DNA Polymerase BETA with template base A and 8oxodGTP in the active site with a dideoxy terminated primer
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-8DG:
8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase / Lyase/DNA / nucleotidyl transferase / DNA polymerase / A:(syn)8oxodGTP / A:C Transversion / Lyase-DNA complex

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