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-Structure paper
Title | 5-Ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-alpha and mTOR for the treatment of breast cancer. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 20, Page 3526-3529, Year 2010 |
Publish date | Apr 13, 2010 (structure data deposition date) |
![]() | Zhang, N. / Ayral-Kaloustian, S. / Anderson, J.T. / Nguyen, T. / Das, S. / Venkatesan, A.M. / Brooijmans, N. / Lucas, J. / Yu, K. / Hollander, I. / Mallon, R. |
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Methods | X-ray diffraction |
Resolution | 2.87 Å |
Structure data | ![]() PDB-3mjw: |
Chemicals | ![]() ChemComp-WYF: |
Source |
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![]() | TRANSFERASE / ATP-binding / Kinase / Nucleotide-binding |