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TitleInsights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 10050-, Year 2010
Publish dateApr 3, 2010 (structure data deposition date)
AuthorsBuchwald, G. / Ebert, J. / Basquin, C. / Sauliere, J. / Jayachandran, U. / Bono, F. / Le Hir, H. / Conti, E.
External linksProc. Natl. Acad. Sci. USA / PubMed:20479275
MethodsX-ray diffraction
Resolution3.4 Å
Structure data

PDB-2xb2:
Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE / EXON JUNCTION COMPLEX / NONSENSE-MEDIATED MRNA DECAY / TRANSLATION / UPF3B

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