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Structure paper

TitleAntibody recognition of a unique tumor-specific glycopeptide antigen.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 10056-10061, Year 2010
Publish dateJul 23, 2009 (structure data deposition date)
AuthorsBrooks, C.L. / Schietinger, A. / Borisova, S.N. / Kufer, P. / Okon, M. / Hirama, T. / Mackenzie, C.R. / Wang, L.X. / Schreiber, H. / Evans, S.V.
External linksProc. Natl. Acad. Sci. USA / PubMed:20479270
MethodsX-ray diffraction
Resolution2.2 - 2.39 Å
Structure data

PDB-3iet:
Crystal Structure of 237mAb with antigen
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3if1:
Crystal structure of 237mAb in complex with a GalNAc
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-A2G:
2-acetamido-2-deoxy-alpha-D-galactopyranose

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-NGA:
2-acetamido-2-deoxy-beta-D-galactopyranose

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / glycopepitde / antibody / Fab / carbohydrate-biding / tumour

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