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TitleInhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation.
Journal, issue, pagesMol. Biosystems, Vol. 6, Page 1682-, Year 2010
Publish dateApr 13, 2010 (structure data deposition date)
AuthorsLowther, J. / Yard, B.A. / Johnson, K.A. / Carter, L.G. / Bhat, V.T. / Raman, M.C.C. / Clarke, D.J. / Ramakers, B. / Mcmahon, S.A. / Naismith, J.H. / Campopiano, D.J.
External linksMol. Biosystems / PubMed:20445930
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-2xbn:
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-PMP:
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • sphingomonas paucimobilis (bacteria)
KeywordsTRANSFERASE / PYRIDOXAL PHOSPHATE

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