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Structure paper

TitleCharacterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino terminal heptad repeat.
Journal, issue, pagesAntiviral Res., Year 2010
Publish dateApr 22, 2010 (structure data deposition date)
AuthorsIzumi, K. / Nakamura, S. / Nakano, H. / Shimura, K. / Sakagami, Y. / Oishi, S. / Uchiyama, S. / Ohkubo, T. / Kobayashi, Y. / Fujii, N. ...Izumi, K. / Nakamura, S. / Nakano, H. / Shimura, K. / Sakagami, Y. / Oishi, S. / Uchiyama, S. / Ohkubo, T. / Kobayashi, Y. / Fujii, N. / Matsuoka, M. / Kodama, E.N.
External linksAntiviral Res. / PubMed:20438763
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-3aha:
Crystal structure of the complex between gp41 fragments N36 and C34 mutant N126K/E137Q
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsMEMBRANE PROTEIN / coiled-coil / VIRAL PROTEIN-INHIBITOR COMPLEX

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