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TitleBasis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 20399-20409, Year 2010
Publish dateApr 21, 2009 (structure data deposition date)
AuthorsHuang, X. / Dementiev, A. / Olson, S.T. / Gettins, P.G.
External linksJ. Biol. Chem. / PubMed:20427285
MethodsX-ray diffraction
Resolution3.26 Å
Structure data

PDB-3h5c:
X-Ray Structure of Protein Z-Protein Z Inhibitor Complex
Method: X-RAY DIFFRACTION / Resolution: 3.26 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-BGC:
beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHydrolase Inhibitor/blood clotting / protein Z-protein Z inhibitor complex / Blood coagulation / Cleavage on pair of basic residues / Disulfide bond / EGF-like domain / Gamma-carboxyglutamic acid / Glycoprotein / Hydroxylation / Secreted / Serine protease homolog / Protease inhibitor / Serine protease inhibitor / Hydrolase Inhibitor-blood clotting complex

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