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Structure paper

TitleInteraction between DNA Polymerase lambda and anticancer nucleoside analogs.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 16874-16879, Year 2010
Publish dateMar 30, 2010 (structure data deposition date)
AuthorsGarcia-Diaz, M. / Murray, M.S. / Kunkel, T.A. / Chou, K.M.
External linksJ. Biol. Chem. / PubMed:20348107
MethodsX-ray diffraction
Resolution1.999 - 2.031 Å
Structure data

PDB-3mda:
DNA polymerase lambda in complex with araC
Method: X-RAY DIFFRACTION / Resolution: 2.031 Å

PDB-3mdc:
DNA polymerase lambda in complex with dFdCTP
Method: X-RAY DIFFRACTION / Resolution: 1.999 Å

Chemicals

ChemComp-PPV:
PYROPHOSPHATE

ChemComp-NA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GTF:
2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate)

Source
  • homo sapiens (human)
KeywordsLyase / Transferase/DNA / protein-DNA complex / Transferase-DNA complex

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