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Structure paper

TitleCrystal Structure of a Cisplatin-(1,3-Gtg) Cross-Link within DNA Polymerase Eta.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 49, Page 3077-, Year 2010
Publish dateSep 16, 2009 (structure data deposition date)
AuthorsReissner, T. / Schneider, S. / Schorr, S. / Carell, T.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:20333640
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-2wtf:
DNA polymerase eta in complex with the cis-diammineplatinum (II) 1,3- GTG intrastrand cross-link
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-DTP:
2'-DEOXYADENOSINE 5'-TRIPHOSPHATE

ChemComp-CA:
Unknown entry

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSFERASE/DNA / TRANSFERASE-DNA COMPLEX / NUCLEOTIDYLTRANSFERASE / TRANSLESION DNA SYNTHESIS / TRANSFERASE / DNA-BINDING / DNA SYNTHESIS / DNA REPLICATION / MUTATOR PROTEIN / DNA DAMAGE / DNA REPAIR

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