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TitleAtomic Resolution Crystallography of a Complex of Triosephosphate Isomerase with a Reaction-Intermediate Analog: New Insight in the Proton Transfer Reaction Mechanism
Journal, issue, pagesProteins, Vol. 78, Page 1878-, Year 2010
Publish dateJul 8, 2008 (structure data deposition date)
AuthorsAlahuhta, M. / Wierenga, R.K.
External linksProteins / PubMed:20235230
MethodsX-ray diffraction
Resolution0.82 Å
Structure data

PDB-2vxn:
E65Q-TIM complexed with phosphoglycolohydroxamate at 0.82 A resolution
Method: X-RAY DIFFRACTION / Resolution: 0.82 Å

Chemicals

ChemComp-PGH:
PHOSPHOGLYCOLOHYDROXAMIC ACID

ChemComp-PGA:
2-PHOSPHOGLYCOLIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • leishmania mexicana (eukaryote)
KeywordsISOMERASE / FATTY ACID BIOSYNTHESIS / TRANSITION STATE ANALOGUE / GLYCOLYSIS / PENTOSE SHUNT / GLUCONEOGENESIS / TIM / GLYCOSOME / TRIOSEPHOSPHATE ISOMERASE / ENZYME-LIGAND COMPLEX / LIPID SYNTHESIS / TRANSITION STATE / PROTONATION STATE

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