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Structure paper

TitleSorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex.
Journal, issue, pagesDev. Cell, Vol. 18, Page 425-436, Year 2010
Publish dateDec 29, 2009 (structure data deposition date)
AuthorsBurgos, P.V. / Mardones, G.A. / Rojas, A.L. / daSilva, L.L. / Prabhu, Y. / Hurley, J.H. / Bonifacino, J.S.
External linksDev. Cell / PubMed:20230749
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-3l81:
Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain, in complex with a sorting peptide from the amyloid precursor protein (APP)
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSPORT PROTEIN / immunoglobulin-like beta-sandwich / Coated pit / Golgi apparatus / Membrane / Phosphoprotein / Protein transport / Transport / Alzheimer disease / Amyloid / Amyloidosis

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