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TitleStructural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases.
Journal, issue, pagesNucleic Acids Res., Year 2010
Publish dateJan 11, 2010 (structure data deposition date)
AuthorsHusain, N. / Tkaczuk, K.L. / Tulsidas, S.R. / Kaminska, K.H. / Cubrilo, S. / Maravic-Vlahovicek, G. / Bujnicki, J.M. / Sivaraman, J.
External linksNucleic Acids Res. / PubMed:20194115
MethodsX-ray diffraction
Resolution2 - 2.1 Å
Structure data

PDB-3lcu:
Crystal Structure of Antibiotic related Methyltransferase
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3lcv:
Crystal Structure of Antibiotic related Methyltransferase
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-HOH:
WATER

ChemComp-SAM:
S-ADENOSYLMETHIONINE

Source
  • micromonospora zionensis (bacteria)
KeywordsTRANSFERASE / Antibiotic Resistance / Methyltransferase

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