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TitleStructural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 13599-13606, Year 2010
Publish dateNov 25, 2009 (structure data deposition date)
AuthorsKozlov, G. / Safaee, N. / Rosenauer, A. / Gehring, K.
External linksJ. Biol. Chem. / PubMed:20181956
MethodsX-ray diffraction
Resolution1.5 - 1.7 Å
Structure data

PDB-3ktp:
Structural basis of GW182 recognition by poly(A)-binding protein
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-3ktr:
Structural basis of ataxin-2 recognition by poly(A)-binding protein
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CD:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / protein-protein complex / Methylation / mRNA processing / mRNA splicing / Nucleus / Phosphoprotein / RNA-binding / Spliceosome / RNA-mediated gene silencing / Translation regulation / Acetylation / Alternative splicing / Cytoplasm / Neurodegeneration / Parkinsonism / Polymorphism / Spinocerebellar ataxia / Triplet repeat expansion

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