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-Structure paper
Title | Selection of a novel and highly specific TNF{alpha} antagonist: insight from the crystal structure of the antagonist-TNF{alpha} complex |
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Journal, issue, pages | J. Biol. Chem., Vol. 285, Page 12096-12100, Year 2010 |
Publish date | Jan 5, 2010 (structure data deposition date) |
Authors | Byla, P. / Andersen, M.H. / Holtet, T.L. / Jacobsen, H. / Munch, M. / Gad, H.H. / Thogersen, H.C. / Hartmann, R. |
External links | J. Biol. Chem. / PubMed:20179326 |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | PDB-3l9j: |
Chemicals | ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / TNF-alpha / antagonist / in vitro selection / Cell membrane / Cytokine / Disulfide bond / Glycoprotein / Lipoprotein / Secreted / Signal-anchor / Transmembrane |