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TitleRole of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 3430-3435, Year 2010
Publish dateNov 24, 2009 (structure data deposition date)
AuthorsGureasko, J. / Kuchment, O. / Makino, D.L. / Sondermann, H. / Bar-Sagi, D. / Kuriyan, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:20133692
MethodsX-ray diffraction
Resolution3.178 Å
Structure data

PDB-3ksy:
Crystal structure of the Histone domain, DH-PH unit, and catalytic unit of the Ras activator Son of Sevenless (SOS)
Method: X-RAY DIFFRACTION / Resolution: 3.178 Å

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Ras / SOS / Ras activator / Son of Sevenless / Disease mutation / Guanine-nucleotide releasing factor

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