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-Structure paper
Title | Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 107, Page 3681-3686, Year 2010 |
Publish date | Nov 9, 2009 (structure data deposition date) |
Authors | Laursen, N.S. / Gordon, N. / Hermans, S. / Lorenz, N. / Jackson, N. / Wines, B. / Spillner, E. / Christensen, J.B. / Jensen, M. / Fredslund, F. ...Laursen, N.S. / Gordon, N. / Hermans, S. / Lorenz, N. / Jackson, N. / Wines, B. / Spillner, E. / Christensen, J.B. / Jensen, M. / Fredslund, F. / Bjerre, M. / Sottrup-Jensen, L. / Fraser, J.D. / Andersen, G.R. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:20133685 |
Methods | X-ray diffraction |
Resolution | 3.6 - 4.2 Å |
Structure data | PDB-3kls: PDB-3km9: |
Chemicals | ChemComp-CD: ChemComp-NAG: |
Source |
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Keywords | IMMUNE SYSTEM / OB-fold / b-grasp domain / FN3 domain / Cleavage on pair of basic residues / Complement alternate pathway / Complement pathway / Cytolysis / Disulfide bond / Glycoprotein / Immune response / Inflammatory response / Innate immunity / Membrane attack complex / Secreted / beta-grasp domain |