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-Structure paper
Title | Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design. |
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Journal, issue, pages | J. Mol. Biol., Vol. 397, Page 508-519, Year 2010 |
Publish date | May 15, 2009 (structure data deposition date) |
Authors | Pappenberger, G. / Benz, J. / Gsell, B. / Hennig, M. / Ruf, A. / Stihle, M. / Thoma, R. / Rudolph, M.G. |
External links | J. Mol. Biol. / PubMed:20132826 |
Methods | X-ray diffraction |
Resolution | 2.15 Å |
Structure data | PDB-3hhd: |
Chemicals | ChemComp-CL: ChemComp-HOH: |
Source |
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Keywords | Transferase / Hydrolase / FATTY ACID SYNTHASE / MULTIENZYME / MEGASYNTHASE / FATTY ACID SYNTHESIS / Acetylation / Cytoplasm / Fatty acid biosynthesis / Lipid synthesis / Lyase / Multifunctional enzyme / NAD / NADP / Oxidoreductase / Phosphopantetheine / Phosphoprotein / Pyridoxal phosphate |