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-Structure paper
タイトル | Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosis. |
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ジャーナル・号・ページ | J. Med. Chem., Vol. 53, Page 1465-1472, Year 2010 |
掲載日 | 2010年1月9日 (構造データの登録日) |
![]() | Wang, S. / Beck, R. / Blench, T. / Burd, A. / Buxton, S. / Malic, M. / Ayele, T. / Shaikh, S. / Chahwala, S. / Chander, C. ...Wang, S. / Beck, R. / Blench, T. / Burd, A. / Buxton, S. / Malic, M. / Ayele, T. / Shaikh, S. / Chahwala, S. / Chander, C. / Holland, R. / Merette, S. / Zhao, L. / Blackney, M. / Watts, A. |
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手法 | X線回折 |
解像度 | 1.9 Å |
構造データ | ![]() PDB-3lc3: |
化合物 | ![]() ChemComp-IYX: ![]() ChemComp-CA: ![]() ChemComp-HOH: |
由来 |
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![]() | Hydrolase/Hydrolase Inhibitor / Protein-Inhibitor complex / Peptidase S1 / Blood coagulation / Calcium / Cleavage on pair of basic residues / Disease mutation / Disulfide bond / EGF-like domain / Gamma-carboxyglutamic acid / Glycoprotein / Hemophilia / Hydrolase / Hydroxylation / Pharmaceutical / Phosphoprotein / Polymorphism / Protease / Secreted / Serine protease / Sulfation / Zymogen / Hydrolase-Hydrolase Inhibitor complex |