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-Structure paper
タイトル | Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening |
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ジャーナル・号・ページ | J. Med. Chem., Vol. 53, Page 1662-1672, Year 2010 |
掲載日 | 2009年9月9日 (構造データの登録日) |
![]() | Ravindranathan, K.P. / Mandiyan, V. / Ekkati, A.R. / Bae, J.H. / Schlessinger, J. / Jorgensen, W.L. |
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手法 | X線回折 |
解像度 | 2.2 Å |
構造データ | ![]() PDB-3js2: |
化合物 | ![]() ChemComp-VM1: ![]() ChemComp-PO4: ![]() ChemComp-HOH: |
由来 |
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![]() | TRANSFERASE / fibroblast growth factor / receptor tyrosine kinase / inhibitor / thienyl nicotinic acid / Alternative splicing / ATP-binding / Chromosomal rearrangement / Craniosynostosis / Disease mutation / Disulfide bond / Dwarfism / Glycoprotein / Heparin-binding / Hypogonadotropic hypogonadism / Immunoglobulin domain / Kallmann syndrome / Kinase / Membrane / Nucleotide-binding / Phosphoprotein / Polymorphism / Receptor / Transmembrane / Tyrosine-protein kinase |