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TitleSolution structure of proinsulin: connecting domain flexibility and prohormone processing.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 7847-7851, Year 2010
Publish dateNov 12, 2009 (structure data deposition date)
AuthorsYang, Y. / Hua, Q.X. / Liu, J. / Shimizu, E.H. / Choquette, M.H. / Mackin, R.B. / Weiss, M.A.
External linksJ. Biol. Chem. / PubMed:20106974
MethodsNMR (solution)
Structure data

PDB-2kqp:
NMR Structure of Proinsulin
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsHORMONE / proinsulin / Carbohydrate metabolism / Cleavage on pair of basic residues / Diabetes mellitus / Disease mutation / Disulfide bond / Glucose metabolism / Pharmaceutical / Secreted

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