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TitleDirect contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 1906-1911, Year 2010
Publish dateNov 30, 2009 (structure data deposition date)
AuthorsYang, Y. / Xie, P. / Opatowsky, Y. / Schlessinger, J.
External linksProc. Natl. Acad. Sci. USA / PubMed:20080685
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-3kvq:
Crystal structure of VEGFR2 extracellular domain D7
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / VEGFR2 / Angiogenesis / ATP-binding / Developmental protein / Differentiation / Glycoprotein / Host-virus interaction / Immunoglobulin domain / Kinase / Membrane / Nucleotide-binding / Phosphoprotein / Polymorphism / Receptor / Transmembrane / Tyrosine-protein kinase

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