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-Structure paper
Title | The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors |
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Journal, issue, pages | J. Med. Chem., Vol. 53, Page 850-854, Year 2010 |
Publish date | Jul 23, 2009 (structure data deposition date) |
![]() | Temperini, C. / Innocenti, A. / Scozzafava, A. / Parkkila, S. / Supuran, C.T. |
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Methods | X-ray diffraction |
Resolution | 2 Å |
Structure data | ![]() PDB-3ieo: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-HG: ![]() ChemComp-AMJ: ![]() ChemComp-BEZ: ![]() ChemComp-HOH: |
Source |
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![]() | LYASE/LYASE INHIBITOR / carbonic anhydrase / antiepilectic / Disease mutation / Lyase / Metal-binding / LYASE-LYASE INHIBITOR complex |