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TitleScreening-Based Discovery of Drug-Like O-Glcnacase Inhibitor Scaffolds
Journal, issue, pagesFEBS Lett., Vol. 584, Page 694-, Year 2010
Publish dateDec 18, 2009 (structure data deposition date)
AuthorsDorfmueller, H.C. / Van Aalten, D.M.F.
External linksFEBS Lett. / PubMed:20026047
MethodsX-ray diffraction
Resolution2.25 Å
Structure data

PDB-2x0y:
Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

Chemicals

ChemComp-X0T:
7-[(2S)-2,3-DIHYDROXYPROPYL]-1,3-DIMETHYL-3,7-DIHYDRO-1H-PURINE-2,6-DIONE

ChemComp-HOH:
WATER

Source
  • clostridium perfringens (bacteria)
KeywordsHYDROLASE / GLYCOSIDASE / CELL ADHESION

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