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Structure paper

TitleCrystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Journal, issue, pagesBiochemistry, Vol. 30, Page 2227-2239, Year 1991
Publish dateNov 6, 1991 (structure data deposition date)
AuthorsBystroff, C. / Kraut, J.
External linksBiochemistry / PubMed:1998681
MethodsX-ray diffraction
Resolution1.9 - 2.3 Å
Structure data

PDB-1dra:
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-1drb:
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-5dfr:
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-MTX:
METHOTREXATE / chemotherapy*YM

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-EOH:
ETHANOL

Source
  • escherichia coli (E. coli)
KeywordsOXIDOREDUCTASE / OXIDO-REDUCTASE

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