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-Structure paper
Title | Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 107, Page 308-313, Year 2010 |
Publish date | Nov 16, 2009 (structure data deposition date) |
![]() | Roymans, D. / De Bondt, H.L. / Arnoult, E. / Geluykens, P. / Gevers, T. / Van Ginderen, M. / Verheyen, N. / Kim, H. / Willebrords, R. / Bonfanti, J.F. ...Roymans, D. / De Bondt, H.L. / Arnoult, E. / Geluykens, P. / Gevers, T. / Van Ginderen, M. / Verheyen, N. / Kim, H. / Willebrords, R. / Bonfanti, J.F. / Bruinzeel, W. / Cummings, M.D. / van Vlijmen, H. / Andries, K. |
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Methods | X-ray diffraction |
Resolution | 1.47 Å |
Structure data | ![]() PDB-3kpe: |
Chemicals | ![]() ChemComp-TM3: ![]() ChemComp-PG4: ![]() ChemComp-HOH: |
Source |
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![]() | VIRAL PROTEIN / FUSION PROTEIN / peptide-small-molecule complex / alpha helix / coiled-coil / Envelope protein / Glycoprotein / Host cell membrane / Host membrane / Lipoprotein / Membrane / Palmitate / Transmembrane / Virion |