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TitleSynthesis, properties, and applications of diazotrifluropropanoyl-containing photoactive analogs of farnesyl diphosphate containing modified linkages for enhanced stability.
Journal, issue, pagesChem. Biol. Drug Des., Vol. 75, Page 51-67, Year 2010
Publish dateNov 23, 2009 (structure data deposition date)
AuthorsHovlid, M.L. / Edelstein, R.L. / Henry, O. / Ochocki, J. / DeGraw, A. / Lenevich, S. / Talbot, T. / Young, V.G. / Hruza, A.W. / Lopez-Gallego, F. ...Hovlid, M.L. / Edelstein, R.L. / Henry, O. / Ochocki, J. / DeGraw, A. / Lenevich, S. / Talbot, T. / Young, V.G. / Hruza, A.W. / Lopez-Gallego, F. / Labello, N.P. / Strickland, C.L. / Schmidt-Dannert, C. / Distefano, M.D.
External linksChem. Biol. Drug Des. / PubMed:19954434
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-3ksl:
Structure of FPT bound to DATFP-DH-GPP
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-SZH:
(2S,6E)-8-{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}-2,6-dimethyloct-6-en-1-yl (2S)-3,3,3-trifluoro-2-hydrazinopropanoate

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsTRANSFERASE / PRENYLTRANSFERASE / Metal-binding / Phosphoprotein / Zinc

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