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Structure paper

TitleStructural characterization of a Protein A mimetic peptide dendrimer bound to human IgG.
Journal, issue, pagesJ. Phys. Chem. B, Vol. 113, Page 16268-16275, Year 2009
Publish dateMay 19, 2008 (structure data deposition date)
AuthorsMoiani, D. / Salvalaglio, M. / Cavallotti, C. / Bujacz, A. / Redzynia, I. / Bujacz, G. / Dinon, F. / Pengo, P. / Fassina, G.
External linksJ. Phys. Chem. B / PubMed:19924842
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-3d6g:
Fc fragment of IgG1 (Herceptin) with protein-A mimetic peptide dendrimer ligand.
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-X12:
2-[[(2S)-2,6-bis[[(2S)-2,6-bis[[(2R)-2-[[(2R,3R)-2-[[(2R)-2-amino-5-carbamimidamido-pentanoyl]amino]-3-hydroxy-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]hexanoyl]amino]ethanoic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fc fragment / IgG1 / glycosilated protein / protein A mimetic peptide dendrimer ligand / Glycoprotein / Immunoglobulin C region / Immunoglobulin domain / Secreted

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