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-Structure paper
Title | Bioisosterism of urea-based GCPII inhibitors: Synthesis and structure-activity relationship studies. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 20, Page 392-397, Year 2010 |
Publish date | Sep 3, 2009 (structure data deposition date) |
![]() | Wang, H. / Byun, Y. / Barinka, C. / Pullambhatla, M. / Bhang, H.E. / Fox, J.J. / Lubkowski, J. / Mease, R.C. / Pomper, M.G. |
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Methods | X-ray diffraction |
Resolution | 2.3 Å |
Structure data | ![]() PDB-3iww: |
Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-CL: ![]() ChemComp-NAG: ![]() ChemComp-YZE: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / prostate specific membrane antigen; metallopeptidase; folate hydrolase; glutamate carboxypeptidase II; Naaladase; urea-based inhibitor / Carboxypeptidase / Cell membrane / Dipeptidase / Glycoprotein / Membrane / Metal-binding / Metalloprotease / Multifunctional enzyme / Protease / Signal-anchor / Transmembrane |