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-Structure paper
Title | Crystal structure of 3-isopropylmalate dehydrogenase in complex with NAD(+) and a designed inhibitor |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 17, Page 7789-7794, Year 2009 |
Publish date | Oct 10, 2008 (structure data deposition date) |
Authors | Nango, E. / Yamamoto, T. / Kumasaka, T. / Eguchi, T. |
External links | Bioorg. Med. Chem. / PubMed:19833522 |
Methods | X-ray diffraction |
Resolution | 2.79 Å |
Structure data | PDB-2ztw: |
Chemicals | ChemComp-NAD: ChemComp-DEI: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / 3-isopropylmalate dehydrogenase / IPMDH / decarboxylating dehydrogenase / Leucine biosynthesis / Amino-acid biosynthesis / Branched-chain amino acid biosynthesis / Cytoplasm / Magnesium / Manganese / Metal-binding / NAD |