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TitleInterplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 131, Page 14932-14937, Year 2009
Publish dateJun 8, 2009 (structure data deposition date)
AuthorsKolarovic, A. / Schweizer, E. / Greene, E. / Gironda, M. / Pallan, P.S. / Egli, M. / Rozners, E.
External linksJ. Am. Chem. Soc. / PubMed:19824732
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-3hr3:
Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-HOH:
WATER

KeywordsDNA / RNA / formacetal-DNA / RNA hydration

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