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Structure paper

TitleStructure and reaction mechanism of human nicotinamide phosphoribosyltransferase
Journal, issue, pagesJ. Biochem., Vol. 147, Page 95-107, Year 2010
Publish dateDec 20, 2006 (structure data deposition date)
AuthorsTakahashi, R. / Nakamura, S. / Nakazawa, T. / Minoura, K. / Yoshida, T. / Nishi, Y. / Kobayashi, Y. / Ohkubo, T.
External linksJ. Biochem. / PubMed:19819904
MethodsX-ray diffraction
Resolution2 - 2.2 Å
Structure data

PDB-2e5b:
Crystal structure of Human NMPRTase as free-form
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-2e5c:
Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2e5d:
Crystal structure of Human NMPRTase complexed with nicotinamide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-PRP:
1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose

ChemComp-NCA:
NICOTINAMIDE / medication*YM

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / NMPRTase / PBEF / Visfatin / PRTase

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