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TitleA Cancer Associated Aurora-A Mutant is Mislocalised and Misregulated due to Loss of Interaction with Tpx2.
Journal, issue, pagesJ. Biol. Chem., Vol. 284, Page 33177-, Year 2009
Publish dateAug 20, 2009 (structure data deposition date)
AuthorsBibby, R.A. / Tang, C. / Faisal, A. / Drosopoulos, K. / Lubbe, S. / Houlston, R. / Bayliss, R. / Linardopoulos, S.
External linksJ. Biol. Chem. / PubMed:19801554
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-2wqe:
Structure of S155R Aurora-A somatic mutant
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / POLYMORPHISM / PHOSPHOPROTEIN / NUCLEOTIDE-BINDING / CELL CYCLE

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