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TitleA constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis.
Journal, issue, pagesBiochem. J., Vol. 424, Page 335-345, Year 2009
Publish dateAug 28, 2009 (structure data deposition date)
AuthorsWalters, J. / Pop, C. / Scott, F.L. / Drag, M. / Swartz, P. / Mattos, C. / Salvesen, G.S. / Clark, A.C.
External linksBiochem. J. / PubMed:19788411
MethodsX-ray diffraction
Resolution1.63 Å
Structure data

PDB-3itn:
Crystal structure of Pseudo-activated Procaspase-3
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / caspase-3 / Apoptosis / Hydrolase / Phosphoprotein / Protease / S-nitrosylation / Thiol protease / Zymogen / HYDROLASE-HYDROLASE INHIBITOR COMPLEX

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