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Structure paper

TitleAbsence of a catalytic water confers resistance to the neurotoxin gabaculine.
Journal, issue, pagesFaseb J., Vol. 24, Page 404-414, Year 2010
Publish dateJan 7, 2009 (structure data deposition date)
AuthorsOrriss, G.L. / Patel, T.R. / Sorensen, J. / Stetefeld, J.
External linksFaseb J. / PubMed:19786580
MethodsX-ray diffraction
Resolution2 - 2.35 Å
Structure data

PDB-3fq7:
Gabaculine complex of GSAM
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-3fq8:
M248I mutant of GSAM
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3fqa:
Gabaculien complex of gabaculine resistant GSAM version
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-PXG:
3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID

ChemComp-HOH:
WATER

ChemComp-PMP:
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE

ChemComp-GAB:
3-AMINOBENZOIC ACID

Source
  • synechococcus elongatus pcc 6301 (bacteria)
KeywordsISOMERASE / Drug resistance / Microevolution / Integrated approach / Chlorophyll biosynthesis / Cytoplasm / Porphyrin biosynthesis / Pyridoxal phosphate / Microev0lution / Microevilution

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